Ebastine (Bastigon) is a potent, long acting and highly selective histamine H1-receptor antagonist. Ebastine, the active ingredient of Bastigon, produces a strong and prolonged selective blocking of the peripheral H1 receptors for histamine. The duration of its action allows administering Bastigon once daily. The drug free from any anticholinergic activity. Since it has no access to central H1 receptor for histamine, it does not show sedative effects. It does not potentiate the effect of alcohol.
Uses Of Ebastine
- Symptomatic treatment of allergic condition.
- Allergic Rhinitis .
- conjunctivitis both Seasonal and perennial,
- Whether or not associated with allergic conductivities (nasal discharge, nasal itching, eye itching, weeping, sneezing, etc)
- Chronic Urticaria, Allergic dermatitis.
Contraindication
Patients with a known hypersensitivity to Ebastine or any of the tablet’s ingredients.
Precautions
Since Ebastine reaches its therapeutic effect 1 to 3 hours after administration, it must not be used
in urgent acute allergic cases.
Interaction
A pharmacokinetic and pharmacodynamic interaction has been observed with ketoconazole or erythromycin. However, no clinically relevant cardiac events have been observed in multicenter double blind clinical trials in patients with allergic rhinitis treated with Ebastine. There is no interaction of Ebastine with Theophylline, Warfarin, Cimetidine, Diazepam or Alcohol.
Warnings
Pregnancy and Lactation : Bastigon should be used during pregnancy only if clearly needed. It is not
known whether Ebastine is excreted in human milk Therefore, Bastigon should not be used during
lactation.
Use in Children
This drug must not be administered to children under 2 years age. Since safety has not been
established in this age group.
Recommended Dose
Allergic rhinitis: Bastigon, at a dose of 10mg once-a-day is efficacious in the relief of the symptoms
of allergic rhinitis, in patient with more severe symptoms including perennial allergic Rhinitis, 20mg
once-a-day provides additional benefit.
Chronic Urticaria:
The adult dose is one 10mg tablet once daily Bastigon can be taken with or without food.
Effects on ability to drive and use machines:
In man psychomotor function has been investigated extensively and no effect was found at
recommended therapeutic doses.
Side Effects
The most commonly reported side- effect, with Bastigon are as follows:
- Headache
- Dry mouth and drowsiness.
- which were comparable to placebo.
- Other less commonly reported side effects include pharyngitis.
- Abdominal pain
- Dyspepsia
Overdose and Treatment
No clinically meaningful signs or symptoms were observed up to 100mg given once daily. If there is
any sign of intoxication proceed to gastric washing and administration of the appropriate
symptomatic maintenance treatment.
Instructions
Store at room temperature (15-25°C), Protect from moisture and sunlight. Keep out of
the reach of children. To be sold on the Description of a registered medical practitioner only.
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FAQ`S ABOUT EBASTINE TABLETS
Can I take Ebastine with other medications?
Before taking Ebastine, inform your doctor about all other medications you are using, including over-the-counter drugs and supplements. Some drugs may interact with Ebastine and affect how it works or increase the risk of side effects.
Can pregnant or breastfeeding women take Ebastine?
- If you are pregnant or planning to become pregnant, consult your doctor before using Ebastine.
- Ebastine should be used with caution during breastfeeding. Discuss with your doctor the potential benefits and risks.
What should I do in case of an overdose?
In case of an overdose, seek immediate medical attention or contact your local poison control center.
Are there any serious side effects to be aware of?
Serious side effects are rare but can include:
- Severe allergic reactions (rash, itching/swelling, severe dizziness, trouble breathing)
- Heart rhythm changes (irregular heartbeat)
Can children take Ebastine tablets?
Ebastine is generally not recommended for children under 12 years of age. Consult your doctor for appropriate alternatives for younger children.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not take a double dose to make up for the missed one.
How should I take Ebastine tablets?
- Follow the dosage instructions provided by your doctor or pharmacist.
- Ebastine tablets are usually taken once a day.
- Swallow the tablet whole with a glass of water.
- It can be taken with or without food.
Disclaimer
The information provided on this platform is for general informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this platform.
